Mechanisms of COPI vesicle formation

被引:37
作者
Hsu, Victor W. [1 ]
Yang, Jia-Shu
机构
[1] Brigham & Womens Hosp, Div Rheumatol Immunol & Allergy, Boston, MA 02115 USA
来源
FEBS LETTERS | 2009年 / 583卷 / 23期
基金
美国国家卫生研究院;
关键词
ADP-ribosylation factor 1; ADP-ribosylation factor GTPase activating protein 1; Brefeldin-A ADP-ribosylated substrate; Coatomer; Coat Protein I; Golgi-specific brefeldin A resistant guanine nucleotide exchange factor 1; NUCLEOTIDE EXCHANGE FACTOR; ADP-RIBOSYLATION FACTOR; I-COATED VESICLES; GUANINE-NUCLEOTIDE; MEMBRANE CURVATURE; BREFELDIN-A; TRANSPORT VESICLES; GOLGI MEMBRANES; BETA-COP; ENDOPLASMIC-RETICULUM;
D O I
10.1016/j.febslet.2009.10.056
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Coat Protein I (COPI) is one of the most intensely investigated coat complexes. Numerous studies have contributed to a general understanding of how coat proteins act to initiate intracellular vesicular transport. This review highlights key recent findings that have shaped our current understanding of how COPI vesicles are formed. (C) 2009 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.
引用
收藏
页码:3758 / 3763
页数:6
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