Trichosporon beigelii infection:: experience in a regional burn center

被引：37

作者：

Cawley, MJ ^{[1
]}

Braxton, GR ^{[1
]}

Haith, LR ^{[1
]}

Reilly, KJ ^{[1
]}

Guilday, RE ^{[1
]}

Patton, ML ^{[1
]}

机构：

[1] Univ Sci Philadelphia, Philadelphia Coll Pharm, Dept Pharm Practice & Pharm Adm, Philadelphia, PA 19104 USA

来源：

BURNS | 2000年 / 26卷 / 05期

关键词：

Trichosporon beigelii; immunocompromised; fungus; amphotericin B; fluconazole; pathogen; resistance;

D O I：

10.1016/S0305-4179(99)00181-3

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Trichosporon beigelii is a fungus once thought to cause only superficial infections, but recently has been increasingly identified as an opportunistic systemic pathogen in immunocompromised patients. There have been very limited reports of this organism in the burn patient population. We describe the first report of pharmacological management of invasive T. beigelii with a combination of amphotericin B and high dose fluconazole in a burn patient. Antifungal susceptibility testing of T. beigelii determined a change in minimum inhibitory concentrations (MICs) of amphotericin B and a consistent resistance pattern with the use of flucytosine. This paper will review our experience with T. beigelii fungus in a regional burn treatment center and review the literature on other experiences in the burn population. (C) 2000 Published by Elsevier Science Ltd and ISBI. All rights reserved.

引用

页码：483 / 486

页数：4

共 36 条

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