Fatigue in Parkinson's disease: a review

被引:241
作者
Friedman, Joseph H.
Brown, Richard G.
Comella, Cynthia
Garber, Carol E.
Krupp, Lauren B.
Lou, Jau-Shin
Marsh, Laura
Nail, Lillian
Shulman, Lisa
Taylor, C. Barr
机构
[1] NeuroHlth, Warwick, RI 02886 USA
[2] Inst Psychiat, London, England
[3] Rush Univ, Med Ctr, Chicago, IL 60612 USA
[4] Northeastern Univ, Boston, MA 02115 USA
[5] SUNY Stony Brook, Stony Brook, NY 11794 USA
[6] Oregon Hlth & Sci Univ, Portland, OR 97201 USA
[7] Johns Hopkins Med Inst, Baltimore, MD 21205 USA
[8] Univ Maryland, Med Ctr, Baltimore, MD 21201 USA
[9] Stanford Univ, Med Ctr, Palo Alto, CA 94304 USA
关键词
fatigue; fatigue in Parkinson's disease; chronic fatigue; primary fatigue; secondary fatigue; depression; apathy; sleepiness; QUALITY-OF-LIFE; SYSTEMIC-LUPUS-ERYTHEMATOSUS; MAJOR DEPRESSIVE DISORDER; TIME PHYSICAL-ACTIVITY; POSITRON-EMISSION-TOMOGRAPHY; INCREASED ENERGY-EXPENDITURE; MULTIPLE-SCLEROSIS PATIENTS; RANDOMIZED CONTROLLED-TRIAL; CANCER-RELATED FATIGUE; DAYTIME SLEEPINESS;
D O I
10.1002/mds.21240
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Fatigue is a common problem in Parkinson's disease (PD), often the most troubling of all symptoms. It is poorly understood, generally under-recognized, and has no known treatment. This article reviews what is known about the symptom, putting it into the context of fatigue in other disorders, and outlines a program for developing better understanding and therapy. (C) 2006 Movement Disorder Society.
引用
收藏
页码:297 / 308
页数:12
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