Sipandinolide:: A butenolide including a novel type of carbon skeleton from Siparuna andina

被引：19

作者：

Jenett-Siems, K

Siems, K

Jakupovic, J

Solis, PN

Gupta, MP

Mockenhaupt, FP

Bienzle, U

Eich, E

机构：

[1] Free Univ Berlin, Inst Pharm Pharmazeut Biol, D-14195 Berlin, Germany

[2] AnalytiCon AG, Potsdam, Germany

[3] Univ Panama, Fac Farm, Ctr Invest Farmacognost Flora Panamena, Panama City, Panama

[4] Humboldt Univ, Med Fak Charite, Inst Trop Med, Berlin, Germany

来源：

PLANTA MEDICA | 2000年 / 66卷 / 04期

关键词：

D O I：

10.1055/s-2000-14898

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

From a lipophilic extract of leaves of Siparuna andina (Monimiaceae), which exhibited antiplasmodial activity in vitro, two new compounds have been isolated: sipandinolide (1), a compound with a novel type of carbon skeleton and (-)-cis-3-acetoxy-4',5,7-trihydroxyflavanone (2). Their structures were established by spectroscopic methods; 2 showed moderate antiplasmodial activity whereas 1 was inactive.

引用

页码：384 / 385

页数：2

共 9 条

[1] 2R,3R-(+)-3-ACETOXY-4',5-DIHYDROXY-7-METHOXYFLAVANONE AND 2R,3R-(+)-3-ACETOXY-4',5,7-TRIHYDROXYFLAVANONE - 2 NEW 3-ACETYLATED DIHYDROFLAVONOLS FROM AFRAMOMUM-PRUINOSUM GAGNEPAIN (ZINGIBERACEAE) [J].