Ionol (BHT) produces superoxide anion

被引：16

作者：

Smirnova, EG

Lyubimov, YI

Malinina, TG

Lyubimova, EY

Alexandrushkina, NI

Vanyushin, BF

Kolesova, GM

Yaguzhinsky, LS ^{[1
]}

机构：

[1] Moscow MV Lomonosov State Univ, Belozersky Inst Physicochem Biol, Moscow 119899, Russia

[2] Russian Acad Agr Sci, Inst Agr Biotechnol, Moscow 127550, Russia

[3] Sci Prod Complex Biotechind, Moscow, Russia

来源：

BIOCHEMISTRY-MOSCOW | 2002年 / 67卷 / 11期

基金：

俄罗斯基础研究基金会;

关键词：

BHT; antioxidant; prooxidant; wheat seedlings; reactive oxygen species; superoxide;

D O I：

10.1023/A:1021357506703

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In aqueous medium etiolated wheat seedlings release superoxide anion (O-2(radical anion)). Interaction of a synthetic antioxidant, butylated hydroxytoluene (BHT, ionol), with oxygen in the aqueous medium is accompanied by O-2(radical anion) formation. This suggests that under certain conditions BHT behaves as a prooxidant. A natural antioxidant, superoxide dismutase (SOD), and also a wound healing preparation, emulsified denatured placenta (EDP), do not exhibit the prooxidant properties. In contrast to BHT, they reduce O-2(radical anion) production by the etiolated wheat seedling system.

引用

页码：1271 / 1275

页数：5

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