Abnormal blood flow and red blood cell deformability in severe malaria

被引：163

作者：

Dondorp, AM

Kager, PA

Vreeken, J

White, NJ

机构：

[1] Acad Med Ctr, Dept Internal Med & Infect Dis, NL-1105 AZ Amsterdam, Netherlands

[2] Acad Med Ctr, Dept Trop Med & AIDS, NL-1105 AZ Amsterdam, Netherlands

[3] Mahidol Univ, Fac Trop Med, Wellcome Mahidol Univ Oxford Trop Med Res Program, Bangkok 10400, Thailand

来源：

PARASITOLOGY TODAY | 2000年 / 16卷 / 06期

关键词：

D O I：

10.1016/S0169-4758(00)01666-5

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

Obstruction of the microcirculation plays a central role in the pathophysiology of severe malaria. Here, Arjen Dondorp and colleagues describe the various contributors to impaired microcirculatory flow in falciparum malaria: sequestration, rosetting and recent findings regarding impaired red blood cell deformability. The correlation with clinical findings and possible therapeutic consequences are discussed.

引用

收藏

页码：228 / 232

页数：5

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