HIV Vaccine Trial Results - An Opening for Further Research

被引：22

作者：

Dolin, Raphael ^{[1
]}

机构：

[1] Harvard Univ, Beth Israel Deaconess Med Ctr, Sch Med, Boston, MA 02215 USA

来源：

NEW ENGLAND JOURNAL OF MEDICINE | 2009年 / 361卷 / 23期

关键词：

DOUBLE-BLIND; COMBINATION; INFECTION; THAILAND;

D O I：

10.1056/NEJMe0909972

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：2279 / 2280

页数：2

共 9 条

[1] Challenges in the development of an HIV-1 vaccine [J].

Barouch, Dan H. .

NATURE, 2008, 455 (7213) :613-619

[2] Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): a double-blind, randomised, placebo-controlled, test-of-concept trial [J].

Buchbinder, Susan P. ;

Mehrotra, Devon V. ;

Duerr, Ann ;

Fitzgerald, Daniel W. ;

Mogg, Robin ;

Li, David ;

Gilbert, Peter B. ;

Lama, Javier R. ;

Marmor, Michael ;

del Rio, Carlos ;

McElrath, M. Juliana ;

Casimiro, Danilo R. ;

Gottesdiener, Keith M. ;

Chodakewitz, Jeffrey A. ;

Corey, Lawrence ;

Robertson, Michael N. .

LANCET, 2008, 372 (9653) :1881-1893

[3] Public health - A sound rationale needed for phase IIIHIV-1 vaccine trials [J].

Burton, DR ;

Desrosiers, RC ;

Doms, RW ;

Feinberg, MB ;

Gallo, RC ;

Hahn, B ;

Hoxie, JA ;

Hunter, E ;

Korber, B ;

Landay, A ;

Lederman, MM ;

Lieberman, J ;

McCune, JM ;

Moore, JP ;

Nathanson, N ;

Picker, L ;

Richman, D ;

Rinaldo, C ;

Stevenson, M ;

Watkins, DI ;

Wolinsky, SM ;

Zack, JA .

SCIENCE, 2004, 303 (5656) :316-316

[4]

CHAN M, 2009, UNIVERSAL ACCESS SCA

[5]

Flynn MN, 2005, J INFECT DIS, V191, P654, DOI 10.1086/428404

[6] Safety and immunogenicity of an HIV subtype B and E prime-boost vaccine combination in HIV-negative Thai adults [J].

Nitayaphan, S ;

Pitisuttithum, P ;

Karnasuta, C ;

Eamsila, C ;

de Souza, M ;

Morgan, P ;

Polonis, V ;

Benenson, M ;

VanCott, T ;

Ratto-Kim, S ;

Kim, J ;

Thapinta, D ;

Garner, R ;

Bussaratid, V ;

Singharaj, P ;

el Habib, R ;

Gurunathan, S ;

Heyward, W ;

Birx, D ;

McNeil, J ;

Brown, AE .

JOURNAL OF INFECTIOUS DISEASES, 2004, 190 (04) :702-706

[7] Randomized, double-blind, placebo-controlled efficacy trial of a bivalent recombinant glycoprotein 120 HIV-1 vaccine among injection drug users in Bangkok, Thailand [J].

Pitisuttithum, Punnee ;

Gilbert, Peter ;

Gurwith, Marc ;

Heyward, William ;

Martin, Michael ;

van Griensven, Fritz ;

Hu, Dale ;

Tappero, Jordan W. ;

Choopanya, Kachit .

JOURNAL OF INFECTIOUS DISEASES, 2006, 194 (12) :1661-1671

[8] Vaccination with ALVAC and AIDSVAX to Prevent HIV-1 Infection in Thailand [J].

Rerks-Ngarm, Supachai ;

Pitisuttithum, Punnee ;

Nitayaphan, Sorachai ;

Kaewkungwal, Jaranit ;

Chiu, Joseph ;

Paris, Robert ;

Premsri, Nakorn ;

Namwat, Chawetsan ;

de Souza, Mark ;

Adams, Elizabeth ;

Benenson, Michael ;

Gurunathan, Sanjay ;

Tartaglia, Jim ;

McNeil, John G. ;

Francis, Donald P. ;

Stablein, Donald ;

Birx, Deborah L. ;

Chunsuttiwat, Supamit ;

Khamboonruang, Chirasak ;

Thongcharoen, Prasert ;

Robb, Merlin L. ;

Michael, Nelson L. ;

Kunasol, Prayura ;

Kim, Jerome H. .

NEW ENGLAND JOURNAL OF MEDICINE, 2009, 361 (23) :2209-2220

[9] Phase 2 study of an HIV-1 canarypox vaccine (vCP1452) alone and in combination with rgp120 - Negative results fail to trigger a phase 3 correlates trial [J].

Russell, Nina D. ;

Graham, Barney S. ;

Keefer, Michael C. ;

McElrath, M. Juliana ;

Self, Steve G. ;

Weinhold, Kent J. ;

Montefiroi, David C. ;

Ferrari, Guido ;

Horton, Helen ;

Tomaras, Georgia D. ;

Gurunathan, Sanjay ;

Baglyos, Lynn ;

Frey, Sharon E. ;

Mulligan, Mark J. ;

Harro, Clayton D. ;

Buchbinder, Susan P. ;

Baden, Lindsey R. ;

Blattner, William A. ;

Koblin, Beryl A. ;

Corey, Lawrence .

JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, 2007, 44 (02) :203-212

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