The vasorelaxant activity of marrubenol and marrubiin from Marrubium vulgare

被引:80
作者
El Bardai, S
Morel, N
Wibo, M
Fabre, N
Llabres, G
Lyoussi, B
Quetin-Leclercq, J
机构
[1] Univ Catholique Louvain, Pharmacol Lab, UCL 5410, B-1200 Brussels, Belgium
[2] Univ Catholique Louvain, Lab Pharmacognosie, B-1200 Brussels, Belgium
[3] Fac Sci Dahar Elmahraz, UFR Physiol Pharmacol, Fes, Morocco
[4] Univ Liege, Dept Phys Exptl, Liege, Belgium
关键词
D O I
10.1055/s-2003-37042
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Crude extracts of the aerial parts of Marrubium vulgare show a potent in vitro inhibition of KCl-induced contraction of rat aorta. Bio-guided fractionations, spectroscopic analysis and chemical derivatization revealed the furanic labdane diterpenes marrubenol and marrubiin as the most active compounds.
引用
收藏
页码:75 / 77
页数:3
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