Antioxidative activity of persimmon and grape seed extract: in vitro and in vivo

被引：140

作者：

Ahn, HS

Jeon, TI

Lee, JY

Hwang, SG

Lim, Y

Park, DK ^{[1
]}

机构：

[1] Konkuk Univ, Dept Appl Biol & Chem, Seoul 143701, South Korea

[2] Hankyong Natl Univ, Dept Dairy Sci, Ansung 456749, South Korea

[3] Konkuk Univ, Bio Mol Informat Ctr, Seoul 143701, South Korea

来源：

NUTRITION RESEARCH | 2002年 / 22卷 / 11期

关键词：

persimmon seeds; tannin; chemiluminescence; lipid peroxidation; antioxidant enzyme; rat;

D O I：

10.1016/S0271-5317(02)00429-3

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 [营养与食品卫生学];

摘要：

We determined in vitro radical scavenging activity of persimmon seed extract (PSE) and grape seed extract (GSE), and quantified total tannin concentrations of each extract. It has been found that both PSE and GSE have radical scavenging activities, and total tannin concentration of PSE was significantly higher than GSE (p < 0.05). In order to investigate the protective effect on oxidative stress in the liver, rats were administered PSE and GSE, respectively. PSE significantly decreased the liver thiobarbituric acid reactive substances (TBARS) and phosphafidylcholine hydroperoxides (PCOOH) level compared to control group (p < 0.05). Furthermore, catalase and superoxide dismutase (SOD) activities were increased by both PSE and GSE administration. However, fatty acid composition in phosphatidylcholine (PC) and phosphatidylethanolamine (PE) were not significantly different among control and other group rats. We concluded that PSE and GSE have strong radical scavenging activity in vitro, and inhibited lipid peroxidation in vivo. (C) 2002 Elsevier Science Inc. All rights reserved.

引用

页码：1265 / 1273

页数：9

共 30 条

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