The function of the proteasome system in MHC class I antigen processing

被引：38

作者：

Stoltze, L

Nussbaum, AK

Sijts, A

Emmerich, NPN

Kloetzel, PM

Schild, H

机构：

[1] Univ Tubingen, Inst Cell Biol, Dept Immunol, D-72076 Tubingen, Germany

[2] Humboldt Univ, Fac Med, Inst Biochem, D-10117 Berlin, Germany

来源：

IMMUNOLOGY TODAY | 2000年 / 21卷 / 07期

关键词：

D O I：

10.1016/S0167-5699(00)01665-0

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

A recent meeting* brought together researchers to discuss the latest developments in the origin and processing of cytotoxic T lymphocyte (CTL) epitopes, with special consideration given to proteasome-related events.

引用

页码：317 / 319

页数：3

共 9 条

[1] Coordinated dual cleavages induced by the proteasome regulator PA28 lead to dominant MHC ligands [J].

Dick, TP ;

Ruppert, T ;

Groettrup, M ;

Kloetzel, PM ;

Kuehn, L ;

Koszinowski, UH ;

Stevanovic, S ;

Schild, H ;

Rammensee, HG .

CELL, 1996, 86 (02) :253-262

[2] CELLULAR PEPTIDE COMPOSITION GOVERNED BY MAJOR HISTOCOMPATIBILITY COMPLEX CLASS-I MOLECULES [J].

FALK, K ;

ROTZSCHKE, O ;

RAMMENSEE, HG .

NATURE, 1990, 348 (6298) :248-251

[3] MHC CLASS-I EXPRESSION IN MICE LACKING THE PROTEASOME SUBUNIT LMP-7 [J].

FEHLING, HJ ;

SWAT, W ;

LAPLACE, C ;

KUHN, R ;

RAJEWSKY, K ;

MULLER, U ;

VONBOEHMER, H .

SCIENCE, 1994, 265 (5176) :1234-1237

[4] A role for the proteasome regulator PA28 alpha in antigen presentation [J].

Groettrup, M ;

Soza, A ;

Eggers, M ;

Kuehn, L ;

Dick, TP ;

Schild, H ;

Rammensee, HG ;

Koszinowski, UH ;

Kloetzel, PM .

NATURE, 1996, 381 (6578) :166-168

[5] Processing of some antigens by the standard proteasome but not by the immunoproteasome results in poor presentation by dendritic cells [J].

Morel, S ;

Lévy, F ;

Burlet-Schiltz, O ;

Brasseur, F ;

Probst-Kepper, M ;

Peitrequin, AL ;

Monsarrat, B ;

Van Velthoven, R ;

Cerottini, JC ;

Boon, T ;

Gairin, JE ;

Van den Eynde, BJ .

IMMUNITY, 2000, 12 (01) :107-117

[6] Impaired immunoproteasome assembly and immune responses in PA28-/- mice [J].

Preckel, T ;

Fung-Leung, WP ;

Cai, ZL ;

Vitiello, A ;

Salter-Cid, L ;

Winqvist, O ;

Wolfe, TC ;

Von Herrath, M ;

Angulo, A ;

Ghazal, P ;

Lee, JD ;

Fourie, AM ;

Wu, Y ;

Pang, J ;

Ngo, K ;

Peterson, PA ;

Früh, K ;

Yang, Y .

SCIENCE, 1999, 286 (5447) :2162-2165

[7]

SIJTS AJA, IN PRESS J IMMUNOL

[8] Efficient generation of a hepatitis B virus cytotoxic T lymphocyte epitope requires the structural features of immunoproteasomes [J].

Sijts, AJAM ;

Ruppert, T ;

Rehermann, B ;

Schmidt, M ;

Koszinowski, U ;

Kloetzel, PM .

JOURNAL OF EXPERIMENTAL MEDICINE, 2000, 191 (03) :503-513

[9] ALTERED PEPTIDASE AND VIRAL-SPECIFIC T-CELL RESPONSE IN LMP2 MUTANT MICE [J].

VANKAER, L ;

ASHTONRICKARDT, PG ;

EICHELBERGER, M ;

GACZYNSKA, M ;

NAGASHIMA, K ;

ROCK, KL ;

GOLDBERG, AL ;

DOHERTY, PC ;

TONEGAWA, S .

IMMUNITY, 1994, 1 (07) :533-541

← 1 →