Photoperiod-temperature and neuroblast proliferation-migration in the adult lizard cortex

被引:40
作者
Ramirez, C
Nacher, J
Molowny, A
SanchezSanchez, F
Irurzun, A
LopezGarcia, C
机构
[1] UNIV VALENCIA,DEPT CELL BIOL,E-46100 BURJASSOT,VALENCIA,SPAIN
[2] UNIV VALENCIA,DEPT GENET,E-46100 BURJASSOT,VALENCIA,SPAIN
[3] UNIV VALENCIA,DEPT PHYSIOL,E-46100 BURJASSOT,VALENCIA,SPAIN
关键词
fascia dentata; lizard hippocampus; neuronal migration; postnatal neurogenesis; photoperiod; regeneration; temperature;
D O I
10.1097/00001756-199707070-00047
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
THE lizard medial cortex (a zone homologous to the mammalian fascia dentata) shows delayed postnatal neurogenesis throughout the lifetime of these animals. Experimental lesioning of this area is followed by neuronal regeneration, a unique phenomenon in the adult amniote telencephalon. The differential effects of temperature and photoperiod on postnatal neurogenetic activity mere studied using tritiated thymidine pulses and posterior autoradiography as well as proliferating cell nuclear antigen (PCNA) immunostaining. Long (summer) photoperiods increased the number of proliferating neuroblasts in the ependymal neuroepithelium. Cold (winter) temperature prevented migration of the newly generated immature neurones.
引用
收藏
页码:2337 / 2342
页数:6
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