RNA-binding proteins as regulators of gene expression

被引:233
作者
Siomi, H [1 ]
Dreyfuss, G [1 ]
机构
[1] UNIV PENN,SCH MED,DEPT BIOCHEM & BIOPHYS,PHILADELPHIA,PA 19104
关键词
D O I
10.1016/S0959-437X(97)80148-7
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
A plethora of post-transcriptional mechanisms are involved in essential steps in the pathway of genetic information expression in eukaryotes. These processes are specified by cis-acting signals on RNAs and are mediated by specific trans-acting factors, including RNA-binding proteins and small complementary RNAs. Recent information has begun to define the molecular mechanisms by which RNA-binding proteins recognize specific RNA sequences and influence the processing and function of RNA molecules.
引用
收藏
页码:345 / 353
页数:9
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