C-reactive protein concentration in canine idiopathic polyarthritis

被引：57

作者：

Ohno, Koichi ^{[1
]}

Yokoyama, Yukiko ^{[1
]}

Nakashima, Ko ^{[1
]}

Setoguchi, Asuka ^{[1
]}

Fujino, Yasuhito ^{[1
]}

Tsujimoto, Hajime ^{[1
]}

机构：

[1] Univ Tokyo, Grad Sch Agr & Life Sci, Dept Vet Internal Med, Bunkyo Ku, Tokyo 1138657, Japan

来源：

JOURNAL OF VETERINARY MEDICAL SCIENCE | 2006年 / 68卷 / 12期

关键词：

canine; C-reactive protein; idiopathic polyarthritis;

D O I：

10.1292/jvms.68.1275

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

To investigate the clinical utility of C-reactive protein (CRP) in idiopathic polyarthritis (IPA), its concentration was measured in dogs with IPA. The CRP concentration was markedly increased in all the IPA dogs at the time of diagnosis and decreased significantly in response to the initial corticosteroid treatment; this indicated that CRP can be used as an index for therapeutic response in IPA cases. Furthermore, at 6 months after the diagnosis, a significant association was observed between the CRP concentration at follow-up (6-13 days after the treatment was started) and the frequency of medication ("no or seldom-medicated (NSM)" groups or "continuing medication (CM)" groups). These results suggest that the initial response of CRP to corticosteroid treatment may be a prognostic factor of canine IPA.

引用

页码：1275 / 1279

页数：5

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