Preparation and antibacterial activity of electrospun chitosan/poly(ethylene oxide) membranes containing silver nanoparticles

被引:144
作者
An, Jing [1 ,2 ,3 ]
Zhang, Hong [1 ,2 ]
Zhang, Jitu [1 ,2 ]
Zhao, Yunhui [1 ,2 ]
Yuan, Xiaoyan [1 ,2 ]
机构
[1] Tianjin Univ, Sch Mat Sci & Engn, Tianjin 300072, Peoples R China
[2] Tianjin Univ, Tianjin Key Lab Composite & Funct Mat, Tianjin 300072, Peoples R China
[3] Hebei Univ Sci & Technol, Coll Sci, Shijiazhuang 050018, Hebei, Peoples R China
关键词
Silver nanoparticles; Chitosan; Poly(ethylene oxide); Electrospinning; Antibacterial activity; MECHANICAL-PROPERTIES; POLYMER NANOFIBERS; SILICA NANOFIBERS; ESCHERICHIA-COLI; CHITOSAN; FABRICATION; MORPHOLOGY; CELLULOSE; STEP;
D O I
10.1007/s00396-009-2108-y
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
Fairly uniform chitosan (CS)/poly(ethylene oxide) (PEO) ultrafine fibers containing silver nanoparticles (AgNPs) were successfully prepared by electrospinning of CS/PEO solutions containing Ag/CS colloids by means of in situ chemical reduction of Ag ions. The presence of AgNPs in the electrospun ultrafine fibers was confirmed by X-ray diffraction patterns. The AgNPs were evenly distributed in CS/PEO ultrafine fibers with the size less than 5 nm observed under a transmission electron microscope. X-ray photoelectron spectroscopy suggested that the existence of AgaEuro center dot O bond in the composite ultrafine fibers led to the tight combination between Ag and CS. Evaluation of antimicrobial activities of the electrospun Ag/CS/PEO fibrous membranes against Escherichia coli showed that the AgNPs in the ultrafine fibers significantly enhanced the inactivation of bacteria.
引用
收藏
页码:1425 / 1434
页数:10
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