Cre-constructing the heart

被引:9
作者
Ruiz-Lozano, P [1 ]
Chien, KR [1 ]
机构
[1] Univ Calif San Diego, Inst Mol Med, La Jolla, CA 92093 USA
关键词
D O I
10.1038/ng0103-8
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
The spatially and temporally coordinated interaction between migratory cardiac precursors, endothelial cells and myogenic precursors leads to the formation of the highly differentiated cell lineages in the heart. In a new study, conditional mouse mutants are used to show that Nf1 signaling in cardiac endothelium is essential for proper heart formation.
引用
收藏
页码:8 / 9
页数:3
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