Identification of the gene encoding the FhbB protein of Treponema denticola, a highly unique factor H-like protein 1 binding protein

被引：30

作者：

McDowell, John V.

Frederick, Jesse

Stamm, Lola

Marconi, Richard T.

机构：

[1] Virginia Commonwealth Univ, Dept Microbiol & Immunol, Richmond, VA 23298 USA

[2] Virginia Commonwealth Univ, Ctr Study Biol Complex, Richmond, VA 23298 USA

[3] Virginia Commonwealth Univ, Med Coll Virginia, Richmond, VA 23298 USA

[4] Univ N Carolina, Dept Epidemiol, Program Infect Dis, Chapel Hill, NC USA

来源：

INFECTION AND IMMUNITY | 2007年 / 75卷 / 02期

关键词：

D O I：

10.1128/IAI.01458-06

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The gene encoding the Treponema denticola factor H-like protein 1 (FHL-1) binding protein, FhbB, was recovered and characterized. Sequence conservation, expression, and properties of FhbB were analyzed. The identification of FhbB represents an important step in understanding the contribution of FHL-1 binding in T. denticola pathogenesis and in development of periodontal disease.

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收藏

页码：1050 / 1054

页数：5

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