Perspectives on protein crystallisation

被引：10

作者：

Ochi, Takashi ^{[2
]}

Bolanos-Garcia, Victor M. ^{[2
]}

Stojanoff, Vivian ^{[3
]}

Moreno, Abel ^{[1
]}

机构：

[1] Univ Nacl Autonoma Mexico, Inst Quim, Mexico City 04510, DF, Mexico

[2] Univ Cambridge, Dept Biochem, Cambridge CB2 1GA, England

[3] Brookhaven Natl Labs, Nsls Upton, NY USA

来源：

PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY | 2009年 / 101卷 / 1-3期

关键词：

DNA-repair proteins; Lif1p-Lig4p; Crystallisation; Gel; Counter-diffusion; Drug discovery; Protein crystal growth; ATOMIC-FORCE MICROSCOPY; FATTY-ACID SYNTHASE; CRYSTAL-GROWTH; X-RAY; MACROMOLECULAR CRYSTALS; RIBOSOMAL-SUBUNITS; MEMBRANE-PROTEINS; GROWING PROTEIN; IN-SITU; NUCLEATION;

D O I：

10.1016/j.pbiomolbio.2009.12.001

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

This final part on 'perspectives' is focused on new strategies that can be used to crystallise proteins and improve the crystal quality of macromolecular complexes using any of the methods reviewed in this focused issue. Some advantages and disadvantages, limitations, and plausible applications to high-resolution X-ray crystallography are discussed. (C) 2009 Elsevier Ltd. All rights reserved.

引用

页码：56 / 63

页数：8

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