Community preparedness for HIV vaccine trials in the Democratic Republic of Congo

被引:19
作者
Olin, John
Kokolamami, Jacques
Lepira, B. Francois
Mwandagalirwa, Kashamuka
Mupenda, Bavon
Ndongala, Michel Lubaki
Maman, Suzanne
Bollinger, Robert
Nachega, Jean
Mokili, John
机构
[1] Johns Hopkins Sch Med, Baltimore, MD USA
[2] VIH SIDA, Programme Natl Lutte, Kinshasa, DR Congo, DEM REP CONGO
[3] Univ Kinshasa, Fac Med, Kinshasa, DR Congo, DEM REP CONGO
[4] Hop Gen Kinshasa, Kinshasa, DR Congo, DEM REP CONGO
[5] Univ Kinshasa, Ctr Bioeth, Ecole Sante Publ, Kinshasa, DR Congo, DEM REP CONGO
[6] McGill Univ, Montreal, PQ H3A 2T5, Canada
[7] Univ N Carolina, Sch Publ Hlth, Chapel Hill, NC 27515 USA
[8] Johns Hopkins Sch Med, Ctr Clin Global Hlth Educ, Baltimore, MD USA
[9] Johns Hopkins Univ, Dept Int Hlth, Baltimore, MD 21218 USA
[10] La Jolla Inst Allergy & Immunol, San Diego, CA USA
关键词
HIV/AIDS; vaccine; clinical trials; community preparedness; stigma;
D O I
10.1080/13691050600888434
中图分类号
D669 [社会生活与社会问题]; C913 [社会生活与社会问题];
学科分类号
1204 ;
摘要
This paper reports on an assessment of community preparedness for HIV vaccine trials in the Democratic Republic of Congo. Formative research was conducted in the capital city of Kinshasa during the period October 2003 to March 2004 to answer questions pertinent to planning trials of a preventive HIV vaccine and to identify related issues. Twenty-seven in-depth interviews and two focus groups were held with potential trial participants and community leaders. Data was collected on the subjects of vaccines, HIV/AIDS and sexual behaviour, and an HIV vaccine. The study also sought to identify factors that motivate a person to volunteer for a vaccine trial or which are disincentives to participation, along with preparedness of the larger community for trials. Personal concerns for health and for the impact of the epidemic on families and country were common motivations for participation. The danger of an experimental vaccine and the stigma of a positive HIV antibody test as the result of vaccination are major concerns and disincentives. The health, educational, and local non-governmental sectors are identified as having important roles to play in assuring preparedness for trials, although significant challenges exist to achieving community preparedness.
引用
收藏
页码:529 / 544
页数:16
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