Modifiers of risk of hereditary breast and ovarian cancer

被引：122

作者：

Narod, SA ^{[1
]}

机构：

[1] Univ Toronto, Womens Coll Hosp, Ctr Res Womens Hlth, Toronto, ON M5G 1N8, Canada

来源：

NATURE REVIEWS CANCER | 2002年 / 2卷 / 02期

关键词：

D O I：

10.1038/nrc726

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Hereditary breast and ovarian cancer is among the most commonly encountered adult genetic disease, and it is increasingly important that geneticists, oncologists, surgeons and gynaecologists are aware of the issues regarding risk assessment, prevention and management of women with inherited susceptibility to cancer. Genetic risk can be modified by external factors, but what are these factors, and how might our knowledge of them help us to better define the risks for individual women and to develop strategies for cancer prevention?

引用

页码：113 / +

页数：12

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