Total synthesis of spicamycin amino nucleoside

被引：34

作者：

Suzuki, T ^{[1
]}

Tanaka, S ^{[1
]}

Yamada, I ^{[1
]}

Koashi, Y ^{[1
]}

Yamada, K ^{[1
]}

Chida, N ^{[1
]}

机构：

[1] Keio Univ, Fac Sci & Technol, Dept Appl Chem, Kohoku Ku, Yokohama, Kanagawa 2238522, Japan

来源：

ORGANIC LETTERS | 2000年 / 2卷 / 08期

关键词：

D O I：

10.1021/ol005715l

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The first total synthesis of spicamycin amino nucleoside 2 has been achieved. The aminoheptose unit 5 was prepared stereoselectively from myo-inositol, and the characteristic N-glycoside linkage was constructed by way of Pd-catalyzed coupling reaction of 5 with 6-chloropurine derivative 6.

引用

页码：1137 / 1140

页数：4

共 18 条

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