Cytotoxic Evaluation of Ag@TiO2 Core-Shell Composite Nanoclusters against Cancer Cells

被引：8

作者：

Abdulla-Al-Mamun, Md. ^{[1
]}

Kusumoto, Yoshihumi ^{[1
]}

Islam, Md. Shariful ^{[1
]}

机构：

[1] Kagoshima Univ, Grad Sch Sci & Engn, Dept Chem & Biosci, Kagoshima 8900065, Japan

来源：

CHEMISTRY LETTERS | 2009年 / 38卷 / 10期

基金：

日本学术振兴会;

关键词：

VISIBLE-LIGHT PHOTOCATALYST; DESTRUCTION;

D O I：

10.1246/cl.2009.980

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A Ag metal core-TiO2 shell (A-@TiO2) composite nanocluster photocatalyst with uniform size and shape was successfully synthesized by a new simple citrate reduction method. The cytotoxicity of colloidal Ag@TiO2 composite nanoclusters was evaluated against cancer (HeLa) cells under UV-vis irradiation. Ag@TiO2 composite nanoclusters were characterized by using UV-vis absorption spectroscopy, TEM, SEM, XPS. XRD, and EDX techniques. It was found that Ag@TiO2 nanoclusters at low concentrations kill HeLa cells by 100%, whereas TiO2 nanoparticles alone kill only ca. 30% at the same concentrations.

引用

页码：980 / 981

页数：2

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