Fluoroquinolone resistance in Salmonella typhi and S-paratyphi A in Bangalore, India

被引：42

作者：

Joshi, S. ^{[1
]}

Amarnath, S. K. ^{[1
]}

机构：

[1] Manipal Hosp, Dept Microbiol, Bangalore 560017, Karnataka, India

来源：

TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE | 2007年 / 101卷 / 03期

关键词：

Salmonella typhi; Salmonella paratyphi A; enteric fever; fluoroquinolones; drug therapy; drug resistance;

D O I：

10.1016/j.trstmh.2006.05.009

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Fluoroquinolone resistance in Salmonella typhi and S. paratyphi A is being increasingly reported. The minimum inhibitory concentrations (MICs) of ciproftoxacin, ofloxacin, levofloxacin and gatifloxacin against S. typhi and S. paratyphi A were compared. Fifty blood culture isolates, 25 S. typhi and 25 S. paratyphi A, were studied. The MICs were determined by the agar dilution method. Disc diffusion was done for the fluoroquinolones and other antibiotics. Nalidixic acid resistance was seen in 21/25 S. paratyphi A and 17/25 S. typhi isolates, and these had higher MICs to fluoroquinolones. Five S. typhi and six S. paratyphi A were fully resistant to ciprofloxacin (MIC > 2 mu g/l). No multidrug resistance was seen in S. typhi. The absence of multidrug resistance and presence of fluoroquinolone resistance warrants a review of therapy for enteric fever. (c) 2006 Royal Society of Tropical Medicine and Hygiene. Published by Elsevier Ltd. All rights reserved.

引用

页码：308 / 310

页数：3

共 9 条

[1] Fluoroquinolone-resistant Salmonella Paratyphi A [J].

Adachi, T ;

Sagara, H ;

Hirose, K ;

Watanabe, H .

EMERGING INFECTIOUS DISEASES, 2005, 11 (01) :172-174

[2]

Colle JG., 1996, Mackie McCarteny's Practical Medical Microbiology 14th Edition, P131

[3]

Hasan R, 2005, LANCET, V366, P1603, DOI 10.1016/S0140-6736(05)67654-4

[4] Clinical outcomes in typhoid fever:: adverse impact of infection with nalidixic acid-resistant Salmonella typhi -: art. no. 37 [J].

Kadhiravan, T ;

Wig, N ;

Kapil, A ;

Kabra, SK ;

Renuka, K ;

Misra, A .

BMC INFECTIOUS DISEASES, 2005, 5 (1)

[5]

Koneman EW., 1997, Color Atlas And Textbook of Diagnostic Microbiology, V5th, P785

[6]

NCCLS (National Committee for Clinical Laboratory Standards), 2002, PERF STAND ANT SUSC

[7] Salmonella paratyphi A rates, Asia [J].

Ochiai, RL ;

Wang, XY ;

von Seidlein, L ;

Yang, J ;

Bhutta, ZA ;

Bhattacharya, SK ;

Agtini, M ;

Deen, JL ;

Wain, J ;

Kim, DR ;

Ali, M ;

Acosta, CJ ;

Jodar, L ;

Clemens, JD .

EMERGING INFECTIOUS DISEASES, 2005, 11 (11) :1764-1766

[8] Enteric fever in Mumbai, India: The good news and the bad news [J].

Rodrigues, C ;

Shenai, S ;

Mehta, A .

CLINICAL INFECTIOUS DISEASES, 2003, 36 (04) :535-535

[9] In vitro activity of gemifloxacin against recent clinical isolates of bacteria in Korea [J].

Yong, D ;

Cheong, HJ ;

Kim, YS ;

Park, YJ ;

Kim, WJ ;

Woo, JH ;

Lee, K ;

Kang, MW ;

Choo, YS .

JOURNAL OF KOREAN MEDICAL SCIENCE, 2002, 17 (06) :737-742

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