Molecular cloning and mapping of a human cDNA (PA2G4) that encodes a protein highly homologous to the mouse cell cycle protein p38-2G4

被引：39

作者：

Lamartine, J

Seri, M

Cinti, R

Heitzmann, F

Creaven, M

Radomski, N

Jost, E

Lenoir, GM

Romeo, G

Sylla, BS

机构：

[1] INT AGCY RES CANC,F-69372 LYON 08,FRANCE

[2] IST GIANNINA GASLINI,GENET MOL LAB,LARGO G GENOVA QUARTO,ITALY

[3] UNIV GIESSEN,D-35390 GIESSEN,GERMANY

来源：

CYTOGENETICS AND CELL GENETICS | 1997年 / 78卷 / 01期

关键词：

D O I：

10.1159/000134621

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

We have identified a novel human gene with strong homology to the mouse Pa2g4 cell cycle gene. This novel gene (called PA2G4) belongs to a gene family with members in several chromosome regions: 3q24-q25, 6q22, 9q21, 12q13, 18q12, 20p12 and Xq25. A composite cDNA of 1697 nucleotides was isolated. The sequence of this cDNA predicts a protein of 394 amino acids. The deduced amino acid sequence of this human protein shows very strong homology to the mouse protein p38-2G4. The cDNA analyzed probably corresponds to a functional copy found at 12q13.

引用

页码：31 / 35

页数：5

共 11 条

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