New 7,20:14,20-diepoxy ent-kauranoids from Isodon xerophilus

被引：51

作者：

Hou, AJ

Li, ML

Jiang, B

Lin, ZW

Ji, SY

Zhou, YP

Sun, HD ^{[1
]}

机构：

[1] Acad Sinica, Kunming Inst Bot, Lab Phytochem, Kunming 650204, Yunnan, Peoples R China

[2] Kunming Med Coll, Lab Pharmacol Nat Prod, Kunming 650031, Yunnan, Peoples R China

来源：

JOURNAL OF NATURAL PRODUCTS | 2000年 / 63卷 / 05期

关键词：

D O I：

10.1021/np9903705

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Three new 7,20:14,20-diepoxy-ent-kaurane diterpenoids, xerophilusins A-C (1-3), together with a known one, macrocalin B (4), were isolated from the leaves of Isodon. xerophilus. Their structures were elucidated on the basis of their spectral properties and X-ray crystallographic analysis. Compounds 1, 2, and 4 showed significant cytotoxic activity against K562, HL-60, and MKN-28 cells.

引用

页码：599 / 601

页数：3

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