A systematic review of intracranial chondrosarcoma and survival

被引:116
作者
Bloch, Orin G. [1 ]
Jian, Brian J. [1 ]
Yang, Isaac [1 ]
Han, Seunggu J. [1 ]
Aranda, Derick [1 ]
Ahn, Brian J. [1 ]
Parsa, Andrew T. [1 ]
机构
[1] Univ Calif San Francisco, Dept Neurol Surg, San Francisco, CA 94143 USA
关键词
Cranial chondrosarcoma; Survival outcomes; Systematic review; EXTRASKELETAL MYXOID CHONDROSARCOMA; SKULL BASE CHONDROSARCOMA; PROTON RADIATION-THERAPY; LOW-GRADE CHONDROSARCOMA; OF-THE-LITERATURE; CRANIAL BASE; MESENCHYMAL CHONDROSARCOMA; TEMPORAL BONE; CARTILAGINOUS TUMORS; SPHENOID SINUS;
D O I
10.1016/j.jocn.2009.05.003
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Most data regarding survival in patients with chondrosarcoma are limited to case studies and small series performed at single institutions. A systematic review was performed to study the relationship between potential prognostic factors and survival. The survival rates were analyzed according to modality of treatment, treatment history, histological subtype, and histological grade. A total of 560 patients with intracranial chondrosarcoma were analyzed. Median follow-up time was 60 months. The 5-year mortality among all patients was 11.5% with median survival of 24 months. Mortality at 5 years was significantly greater for patients with tumors of higher grade, or of the mesenchymal subtype, or who had received surgical resection alone. The results of our systematic review Provide useful data in predicting survival among intracranial chondrosarcoma patients. Published by Elsevier Ltd.
引用
收藏
页码:1547 / 1551
页数:5
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