Highly pathogenic avian influenza virus subtype H5N1 in Mute swans in the Czech Republic

被引:45
作者
Nagy, Alexander
Machova, Jirina
Hornickova, Jitka
Tomci, Miroslav
Nagl, Ivan
Horyna, Bedrich
Holko, Ivan
机构
[1] State Vet Inst Prague, Natl Reference Lab Avian Influenza, Prague 16503 6, Czech Republic
[2] State Vet Inst Prague, Dept Pathol, Prague 16503 6, Czech Republic
关键词
highly pathogenic avian influenza; H5N1; Mute swan; bird flu; influenza A;
D O I
10.1016/j.vetmic.2006.10.004
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
In order to determine the actual prevalence of avian influenza viruses (AIV) in wild birds in the Czech Republic extensive surveillance was carried out between January and April 2006. A total of 2101 samples representing 61 bird species were examined for the presence of influenza A by using PCR, sequencing and cultivation on chicken embryos. AIV subtype H5N1 was detected in 12 Mute swans (Cygnus olor). The viruses were determined as HPAI (highly pathogenic avian influenza) and the hemagglutinin sequence was closely similar to A/mallard/Italy/835/06 and A/turkey/Turkey/1194/05. Following the first H5N1 case, about 300 wild birds representing 33 species were collected from the outbreak region and tested for the presence of AIV without any positive result. This is the first report of highly pathogenic avian influenza subtype H5N1 in the Czech Republic. The potential role of swan as an effective vector of avian influenza virus is also discussed. (c) 2006 Elsevier B.V. All rights reserved.
引用
收藏
页码:9 / 16
页数:8
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