CD4+ lymphocyte-mediated suppression of cytomegalovirus expression in human astrocytes

被引：2

作者：

Cheerin, MCJ

Gekker, G

Hu, SX

Yager, SL

Peterson, PK

Lokensgard, JR

机构：

[1] Minneapolis Med Res Fdn, Inst Brain & Immune Disorders, Minneapolis, MN 55404 USA

[2] Univ Minnesota, Sch Med, Minneapolis, MN 55404 USA

[3] Univ Minnesota, Coll Vet Med, St Paul, MN 55108 USA

来源：

CLINICAL AND DIAGNOSTIC LABORATORY IMMUNOLOGY | 2000年 / 7卷 / 04期

关键词：

D O I：

10.1128/CDLI.7.4.710-713.2000

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Cytomegalovirus-stimulated CD4(+) lymphocytes from seropositive but not seronegative donors suppressed viral gene expression in primary human astrocytes. This suppressive activity was mediated through soluble factors. These findings suggest that CD4(+) lymphocytes play a role in defense of the brain against cytomegalovirus.

引用

页码：710 / 713

页数：4

共 31 条

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[4]

2-X