Heterocyclic synthesis by C-C bond formation. Tetrahydrofuran and tetrahydropyran synthesis via oxonium ion-mediated cyclisation reactions

被引：9

作者：

Craig, D ^{[1
]}

King, NP ^{[1
]}

Shaw, AN ^{[1
]}

机构：

[1] SMITHKLINE BEECHAM PHARMACEUT LTD,WELWYN GARDEN CIT AL6 9AR,HERTS,ENGLAND

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 49期

基金：

英国工程与自然科学研究理事会;

关键词：

D O I：

10.1016/S0040-4039(97)10294-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Dimethyl(methylthio)sulfonium tetrafluoroborate triggers ionisation and cyclisation of hemithioacetals 3 to give tetrahydrofurans 8-11 in good yields and stereoselectivities. The homologous sulfone analogues 17 give tetrahydropyrans on treatment with ethylaluminium dichloride. (C) 1997 Elsevier Science Ltd.

引用

页码：8599 / 8602

页数：4

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