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Quantitative aspects of brain perfusion dynamic induced by bold fMRI

被引：17
作者：
Andrade, Katia C.
Pontes-Neto, Octavio M.
Leite, Joao P.
Santos, Antonio Carlos
Baffa, Oswaldo
de Araujo, Draulio B.
机构：
[1] Univ Sao Paulo, Dept Math & Phys, FFCLRP, BR-14040901 Ribeirao Preto, SP, Brazil
[2] USP, Dept Math & Phys, FFCLRP, BR-14040901 Ribeirao Preto, SP, Brazil
[3] USP, Dept Internal Med, FMRP, BR-1404090 Ribeirao Preto, SP, Brazil
[4] USP, Dept Neurol, FMRP, BR-1404090 Ribeirao Preto, SP, Brazil
来源：
ARQUIVOS DE NEURO-PSIQUIATRIA | 2006年 / 64卷 / 04期
关键词：
functional MRI; fMRI; BOLD; perfusion;
D O I：
10.1590/S0004-282X2006000600001
中图分类号：
Q189 [神经科学];
学科分类号：
071006 [神经生物学];
摘要：
The increase of relative cerebral blood flow (rCBF) may contribute for a change in blood oxygenation level dependent signal (BOLD). The main purpose of this study is to investigate some aspects of perfusional alterations in the human brain in response to a uniform stimulation: hypercapnia induced by breath holding. It was observed that the BOLD signal increased globally during hypercapnia and that it is correlated with the time of breath holding. This signal increase shows a clear distinction between gray and white matter, being greater in the grey matter.
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页码：895 / 898
页数：4
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