Transabdominal ultrasound-guided embryo transfer does not increase pregnancy rates in oocyte recipients

被引:43
作者
García-Velasco, JA [1 ]
Isaza, V [1 ]
Martinez-Salazar, J [1 ]
Landazábal, A [1 ]
Requena, A [1 ]
Remohí, J [1 ]
Pellicer, A [1 ]
Simón, C [1 ]
机构
[1] IVI Madrid, Madrid 28035, Spain
关键词
ultrasound-guided embryo transfer; oocyte donation;
D O I
10.1016/S0015-0282(02)03249-1
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Objective: To determine whether transabdominal ultrasound guidance during embryo transfer (ET) is a useful tool for increasing pregnancy rates in patients undergoing oocyte donation. Design: Prospective, randomized, controlled trial. Setting: In vitro fertilization academic center. Patient(s): Three hundred seventy-four infertile patients undergoing oocyte donation. Intervention(s): Transabdominal ultrasound-guided ET. Main Outcome Measure(s): We measured the pregnancy rate and implantation rate after transabdominal ultrasound-guided ET versus the rates in a control group who did not receive transabdominal ultrasound-guided ET. Result(s): Clear visualization at ultrasound during ET was achieved in 90.8% of the patients who had ultrasound-guided ET. A similar number of easy transfers were performed in both the ultrasound-guided and the control groups (84.5% vs. 86.6%). The pregnancy rate was comparable between the groups (59.9% ultrasound vs. 55.1% control), as was the implantation rate (30.6% ultrasound vs. 26.3% control). No differences were found in the miscarriage rate (10.7% ultrasound vs. 9.1% control) or in the multiple pregnancy rate (21.4% ultrasound vs. 22.5% control). Although all ectopic pregnancies occurred in the group that did not receive ultrasound guidance, the differences were not statistically significant (0 vs. 2.7%). Conclusion(s): We could not show any benefit in terms of pregnancy rate in oocyte recipients for whom ET was performed under direct transabdominal ultrasound visualization of the endometrial cavity. There was a lower ectopic pregnancy rate when ultrasound guidance was used, but this rate was not statistically significant in comparison with the pregnancy rate without ultrasound guidance. (C) 2002 by American Society for Reproductive Medicine.
引用
收藏
页码:534 / 539
页数:6
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