Bioactive paper provides a low-cost platform for diagnostics

被引:460
作者
Pelton, Robert [1 ]
机构
[1] McMaster Univ, Dept Chem Engn, Hamilton, ON L8S 4L7, Canada
基金
加拿大自然科学与工程研究理事会;
关键词
Antibody; Antimicrobial paper; Bacteriophage; Bioactive paper; Biosensor; DNA aptamer; Lateral flow; Paperfluidics; Paper-supported assay; Pathogen detection; HORSERADISH-PEROXIDASE; MICROFLUIDIC DEVICES; BIOTINYLATED DNA; FUSION PROTEINS; CELLULOSE; IMMOBILIZATION; ADSORPTION; GOLD; BINDING; POLYMERS;
D O I
10.1016/j.trac.2009.05.005
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Bioactive paper includes a range of potential paper-based materials that can perform analytical functions normally reserved for multi-well plates in the laboratory or for portable electronic devices. Pathogen detection is the most compelling application. Simple paper-based detection, not requiring hardware, has the potential to have impacts in society, ranging from the kitchen to disasters in the developing world. Bioactive-paper research is an emerging field with significant efforts in Canada, USA (Harvard), Finland and Australia. Following a brief introduction to the material and surface properties of paper, I review the literature. Some of the early work exploits the porosity of paper to generate paper-based microfluidics ("paperfluidics") devices. I exclude from this review printed electronic devices and plastics-supported devices. (c) 2009 Elsevier Ltd. All rights reserved.
引用
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页码:925 / 942
页数:18
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