Blood-Brain Barrier Disruption by Continuous-Wave Radio Frequency Radiation

被引:29
作者
Sirav, Bahriye [1 ]
Seyhan, Nesrin [1 ]
机构
[1] Gazi Univ, Fac Med, Dept Biophys, Gazi Nonionizing Radiat Protect Ctr, TR-06510 Ankara, Turkey
关键词
Blood brain barrier; Evans Blue; Radio frequency radiation; Rats; Mobile phones; MOBILE PHONE USE; ENDOTHELIAL-CELLS; OXIDATIVE STRESS; PERMEABILITY; SYSTEM; TELEPHONES; SYMPTOMS; EXPOSURE; SUCROSE; FIELDS;
D O I
10.1080/15368370802608738
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
The increasing use of cellular phones and the increasing number of associated base stations are becoming a widespread source of non ionizing electromagnetic radiation. Some biological effects are likely to occur even at low-level EM fields. This study was designed to investigate the effects of 900 and 1,800 MHz Continuous Wave Radio Frequency Radiation (CW RFR) on the permeability of Blood Brain Barrier (BBB) of rats. Results have shown that 20 min RFR exposure of 900 and 1,800 MHz induces an effect and increases the permeability of BBB of male rats. There was no change in female rats. The scientific evidence on RFR safety or harm remains inconclusive More studies are needed to demonstrate the effects of RFR on the permeability of BBB and the mechanisms of that breakdown.
引用
收藏
页码:215 / 222
页数:8
相关论文
共 35 条
[1]  
Ahlbom A, 1998, HEALTH PHYS, V74, P494
[2]   Headaches from cellular telephones: Are they real and what are the implications? [J].
Frey, AH .
ENVIRONMENTAL HEALTH PERSPECTIVES, 1998, 106 (03) :101-103
[3]   Effect of global system for mobile communication (GSM) microwave exposure on blood-brain barrier permeability in rat [J].
Fritze, K ;
Sommer, C ;
Schmitz, B ;
Mies, G ;
Hossmann, KA ;
Kiessling, M ;
Wiessner, C .
ACTA NEUROPATHOLOGICA, 1997, 94 (05) :465-470
[4]   Dielectric properties of biological tissue: Variation with age [J].
Gabriel, C .
BIOELECTROMAGNETICS, 2005, :S12-S18
[5]   ABSENCE OF MICROWAVE EFFECT ON BLOOD-BRAIN-BARRIER PERMEABILITY TO [C-14]-LABELED SUCROSE IN THE CONSCIOUS RAT [J].
GRUENAU, SP ;
OSCAR, KJ ;
FOLKER, MT ;
RAPOPORT, SI .
EXPERIMENTAL NEUROLOGY, 1982, 75 (02) :299-307
[6]   Mobile phone use and risk of glioma in adults - Results are difficult to interpret because of limitations [J].
Hardell, L ;
Mild, KH .
BRITISH MEDICAL JOURNAL, 2006, 332 (7548) :1035-1035
[7]   Ginkgo biloba prevents mobile phone-induced oxidative stress in rat brain [J].
Ilhan, A ;
Gurel, A ;
Armutcu, F ;
Kamisli, S ;
Iraz, M ;
Akyol, O ;
Ozen, S .
CLINICA CHIMICA ACTA, 2004, 340 (1-2) :153-162
[8]   LYMPHOCYTE INFILTRATION INTO NORMAL RAT-BRAIN FOLLOWING HYPEROSMOTIC BLOOD-BRAIN-BARRIER OPENING [J].
KAJIWARA, K ;
ITO, H ;
FUKUMOTO, T .
JOURNAL OF NEUROIMMUNOLOGY, 1990, 27 (2-3) :133-140
[9]   Catalase and α-tocopherol attenuate blood-brain barrier breakdown in pentylenetetrazole-induced epileptic seizures in acute hyperglycaemic rats [J].
Kalayci, R ;
Kaya, M ;
Kucuk, M ;
Cimen, V ;
Arican, N ;
Gurses, C ;
Elmas, I .
PHARMACOLOGICAL RESEARCH, 2002, 45 (02) :129-133
[10]   POLYAMINES AND CA-2+ MEDIATE HYPEROSMOLAL OPENING OF THE BLOOD-BRAIN-BARRIER - INVITRO STUDIES IN ISOLATED RAT CEREBRAL CAPILLARIES [J].
KOENIG, H ;
GOLDSTONE, AD ;
LU, CY ;
TROUT, JJ .
JOURNAL OF NEUROCHEMISTRY, 1989, 52 (04) :1135-1142