Characterization of the CtsR Stress Response Regulon in Lactobacillus plantarum

被引：62

作者：

Fiocco, Daniela ^{[2
]}

Capozzi, Vittorio ^{[1
]}

Collins, Michael ^{[5
]}

Gallone, Anna ^{[2
]}

Hols, Pascal ^{[3
]}

Guzzo, Jean ^{[4
]}

Weidmann, Stephanie ^{[4
]}

Rieu, Aurelie ^{[4
]}

Msadek, Tarek ^{[5
]}

Spano, Giuseppe ^{[1
]}

机构：

[1] Univ Foggia, Dept Food Sci, I-71100 Foggia, Italy

[2] Univ Foggia, Dept Biomed Sci, I-71100 Foggia, Italy

[3] Catholic Univ Louvain, ISV, Unite Genet, B-1348 Louvain, Belgium

[4] Univ Bourgogne, Inst Jules Guyot, REVV, Dijon, France

[5] CNRS, Dept Microbiol, Inst Pasteur, URA 2172, F-75724 Paris 15, France

来源：

JOURNAL OF BACTERIOLOGY | 2010年 / 192卷 / 03期

关键词：

TRANSCRIPTION QUANTITATIVE PCR; COMPLETE GENOME SEQUENCE; NEGATIVE REGULATOR; INTERNAL CONTROL; GENE-EXPRESSION; SHOCK; HEAT; GROWTH; IDENTIFICATION; TOLERANCE;

D O I：

10.1128/JB.01122-09

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Lactobacillus plantarum ctsR was characterized. ctsR was found to be cotranscribed with clpC and induced in response to various abiotic stresses. ctsR deletion conferred a heat-sensitive phenotype with peculiar cell morphological features. The transcriptional pattern of putative CtsR regulon genes was examined in the Delta ctsR mutant. Direct CtsR-dependent regulation was demonstrated by DNA-binding assays using recombinant CtsR and the promoters of the ctsR-clpC operon and hsp1.

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页码：896 / 900

页数：5

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