Effect of supplemental oral L-arginine on exercise capacity in patients with stable angina pectoris

被引:121
作者
Ceremuzynski, L
Chamiec, T
HerbaczynskaCedro, K
机构
[1] POLISH ACAD SCI,MED RES CTR,WARSAW,POLAND
[2] POSTGRAD MED SCH,DEPT CARDIOL,WARSAW,POLAND
关键词
D O I
10.1016/S0002-9149(97)00354-8
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
A randomized, double-blind, placebo-controlled study in patients with clinical symptoms of stable angina pectoris and healed myocardial infarction (n = 22) has shown that oral supplementation with L-arginine (6 g/day for 3 days) increases exercise capacity (tested on a Marquette case 12 treadmill according to the modified Bruce protocol). Results suggest that the inefficient L-arginine/nitric oxide system contributes to limitation of myocardial perfusion and/or peripheral vasodilation during maximum exercise in patients with stable angina pectoris.
引用
收藏
页码:331 / &
页数:7
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