The Kraepelinian dichotomy - going, going ... but still not gone

被引：383

作者：

Craddock, Nick ^{[1
]}

Owen, Michael J. ^{[1
]}

机构：

[1] Cardiff Univ, Sch Med, Ctr Neuropsychiat Genet & Genom, Cardiff CF14 4XN, Wales

来源：

BRITISH JOURNAL OF PSYCHIATRY | 2010年 / 196卷 / 02期

基金：

英国惠康基金; 英国医学研究理事会;

关键词：

GENOME-WIDE ASSOCIATION; SCHIZOAFFECTIVE DISORDER; BIPOLAR DISORDER; SCHIZOPHRENIA; VARIANTS; GENETICS; 16P11.2;

D O I：

10.1192/bjp.bp.109.073429

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

Recent genetic studies reinforce the view that current approaches to the diagnosis and classification of major psychiatric illness are inadequate. These findings challenge the distinction between schizophrenia and bipolar disorder, and suggest that more attention should be given to the relationship between the functional psychoses and neurodevelopmental disorders such as autism. We are entering a transitional period of several years during which psychiatry will need to move from using traditional descriptive diagnoses to clinical entities (categories and/or dimensions) that relate more closely to the underlying workings of the brain.

引用

页码：92 / 95

页数：4

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