Knockout Rats via Embryo Microinjection of Zinc-Finger Nucleases

被引:679
作者
Geurts, Aron M. [1 ,2 ]
Cost, Gregory J. [3 ]
Freyvert, Yevgeniy [3 ]
Zeitler, Bryan [3 ]
Miller, Jeffrey C. [3 ]
Choi, Vivian M. [3 ]
Jenkins, Shirin S. [3 ]
Wood, Adam [4 ]
Cui, Xiaoxia [4 ]
Meng, Xiangdong [3 ]
Vincent, Anna [3 ]
Lam, Stephen [3 ]
Michalkiewicz, Mieczyslaw [1 ,2 ]
Schilling, Rebecca [1 ,2 ]
Foeckler, Jamie [3 ]
Kalloway, Shawn [3 ]
Weiler, Hartmut [1 ,2 ]
Menoret, Severine [5 ]
Anegon, Ignacio [5 ]
Davis, Gregory D. [4 ]
Zhang, Lei [3 ]
Rebar, Edward J. [3 ]
Gregory, Philip D. [3 ]
Urnov, Fyodor D. [3 ]
Jacob, Howard J. [1 ,2 ,6 ]
Buelow, Roland [7 ]
机构
[1] Med Coll Wisconsin, Human & Mol Genet Ctr, Milwaukee, WI 53226 USA
[2] Med Coll Wisconsin, Dept Physiol, Milwaukee, WI 53226 USA
[3] Sangamo BioSci Inc, Richmond, CA 94804 USA
[4] Sigma Aldrich Biotechnol, St Louis, MO 63103 USA
[5] Univ Nantes, CHU Nantes, INSERM, UMR 643, F-44322 Nantes, France
[6] Med Coll Wisconsin, Dept Pediat, Milwaukee, WI 53226 USA
[7] Open Monoclonal Technol Inc, Palo Alto, CA 94303 USA
关键词
PROSPECTS; PROGRESS;
D O I
10.1126/science.1172447
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
引用
收藏
页码:433 / 433
页数:1
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