Microwave-promoted esterification reactions: Optimization and scale-up

被引：28

作者：

Amore, Kristen M. ^{[1
]}

Leadbeater, Nicholas E. ^{[1
]}

机构：

[1] Univ Connecticut, Dept Chem, Storrs, CT 06269 USA

来源：

MACROMOLECULAR RAPID COMMUNICATIONS | 2007年 / 28卷 / 04期

关键词：

esterification; microwave heating; radiation; scale-up;

D O I：

10.1002/marc.200600751

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

Microwave heating is becoming a widely accepted tool for synthetic chemists. While many reactions have been performed on a small scale using microwave heating, few have been further developed into larger-scale syntheses. Here, a microwave-promoted esterification reaction protocol is presented. The apparatus used allows for the removal of water generated during the course of the reaction and as a result the process can be driven toward completion. Reactions have been run on scales up to 3 mol.

引用

页码：473 / 477

页数：5

共 49 条

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