Serum levels of soluble form of Fas molecule in patients with congestive heart failure

被引：67

作者：

Okuyama, M

Yamaguchi, S

Nozaki, N

Yamaoka, M

Shirakabe, M

Tomoike, H

机构：

[1] First Dept. of Internal Medicine, Yamagata University Medical School, Yamagata

来源：

AMERICAN JOURNAL OF CARDIOLOGY | 1997年 / 79卷 / 12期

关键词：

D O I：

10.1016/S0002-9149(97)00228-2

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Compared with soluble Fas molecule (sFas, an inhibitor of Fas-mediated apoptosis) in normal volunteers, the serum level of sFas significantly increased by 41% in New York Heart Association (NYHA) class III (p < 0.05) and by 97% in NYHA class IV patients with congestive heart failure (p < 0.001). Furthermore, sFas showed correlations with soluble forms of TNF receptor-p55 (RI) and -p75 (RII) (r = 0.68 and r = 0.56) which inhibit activities of TNF alpha.

引用

页码：1698 / &

页数：6

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[21] 2 TUMOR-NECROSIS-FACTOR RECEPTORS - STRUCTURE AND FUNCTION [J].