IVIG therapy:: Interfering with interferon-γ

被引:24
作者
Clynes, Raphael [1 ]
机构
[1] Columbia Univ, Dept Med & Microbiol, New York, NY 10032 USA
关键词
D O I
10.1016/j.immuni.2007.01.006
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
The immunosuppressive mechanism of action of intravenous immune globulin (IVIG) has remained enigmatic despite the many years of clinical experience in the treatment of autoimmunity. In this issue of Immunity, Park-Min et al. (2007) demonstrate that IVIG engagement of Fc gamma RIII receptor on monocytes inhibits the cellular response to interferon-gamma.
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页码:4 / 6
页数:3
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