Protein phosphatase 2A: a definite player in viral and parasitic regulation

被引:24
作者
Garcia, A
Cayla, X
Sontag, E
机构
[1] Inst Pasteur, Dept Immunol, Lab Signalisat Immunoparasitaire, F-75015 Paris, France
[2] INRA, CNRS, Reprod Physiol Lab, F-75005 Paris, France
[3] Univ Texas, SW Med Ctr, Dept Pathol, Dallas, TX 75235 USA
关键词
Ser/thr phosphatases; PP2A; virus; parasites;
D O I
10.1016/S1286-4579(00)00327-0
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Cells use phosphorylation/dephosphorylation mechanisms to regulate the activity of several proteins required to transmit information from the cell surface to the nucleus. Recent studies have significantly increased our knowledge regarding the structure/function of one major regulator of cell phosphorylation: protein phosphatase 2A (PP2A). This review will discuss the role of PP2A in virology and parasitology. (C) 2000 Editions scientifiques er medicales Elsevier SAS.
引用
收藏
页码:401 / 407
页数:7
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