Metabolism of linoleic acid by human gut bacteria: Different routes for biosynthesis of conjugated linoleic acid

被引:212
作者
Devillard, Estelle [1 ]
McIntosh, Freda M. [1 ]
Duncan, Sylvia H. [1 ]
Wallace, R. John [1 ]
机构
[1] Rowett Res Inst, Gut Hlth Div, Aberdeen AB21 9SB, Scotland
关键词
D O I
10.1128/JB.01359-06
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
A survey of 30 representative strains of human gram-positive intestinal bacteria indicated that Roseburia species were among the most active in metabolizing linoleic acid (cis-9,cis-12-18:2). Different Roseburia spp. formed either vaccenic acid (trans-11-18:1) or a 10-hydroxy-18:1; these compounds are precursors of the health-promoting conjugated linoleic acid cis-9,trans-11-18:2 in human tissues and the intestine, respectively.
引用
收藏
页码:2566 / 2570
页数:5
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