Birth weight and cognitive function in young adult life: historical cohort study

被引：161

作者：

Sorensen, HT

Sabroe, S

Olsen, J

Rothman, KJ

Gillman, MW

Fischer, P

机构：

[1] AARHUS UNIV HOSP,DEPT INTERNAL MED 5,DK-8000 AARHUS C,DENMARK

[2] BOSTON UNIV,SCH MED,DEPT EPIDEMIOL & PREVENT MED,BOSTON,MA 02118

[3] HARVARD UNIV,SCH MED,DEPT AMBULATORY CARE & PREVENT,BOSTON,MA 02215

[4] HARVARD PILGRIM HLTH CARE,BOSTON,MA 02215

[5] CONSCRIPT ADM,COUNTY N JUTLAND,DK-9000 AALBORG,DENMARK

来源：

BRITISH MEDICAL JOURNAL | 1997年 / 315卷 / 7105期

关键词：

D O I：

10.1136/bmj.315.7105.401

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Objective: To examine the relation between birth weight and cognitive function in young adult life. Design: Retrospective cohort study based on birth registry data and cognitive function measured during evaluation for military service. Subjects: 4300 Danish conscripts born between 1973 and 1975. Main outcome measures: Mean score in the Boerge Prien test of cognitive function; score is the number of correct answers to 78 questions and correlates with full scale intelligence quotient (IQ). Results: Mean score in the Boerge Prien test increased from 39.9 at a birth weight of less than or equal to 2500 g to 44.6 at a birth weight of 4200 g even after adjustment for gestational age and length at birth, maternal age and parity and other variables. Above a birth weight of 4200 g the test score decreased slightly. Conclusion: Birth weight is associated with cognitive performance in young adult life, Interference with fetal growth may influence adult cognitive performance.

引用

页码：401 / 403

页数：3

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Barker D.J. P., 1994, MOTHERS BABIES DIS L

[2]

ELARDO R, 1975, CHILD DEV, V46, P71

[3] DOSE-RESPONSE AND TREND ANALYSIS IN EPIDEMIOLOGY - ALTERNATIVES TO CATEGORICAL ANALYSIS [J].