Guillain-Barre syndrome in northwest Greece

被引:25
作者
Markoula, S. [1 ]
Giannopoulos, S. [1 ]
Sarmas, I. [1 ]
Tzavidi, S. [1 ]
Kyritsis, A. P. [1 ]
Lagos, G. [1 ]
机构
[1] Univ Ioannina, Dept Neurol, Sch Med, GR-45110 Ioannina, Greece
来源
ACTA NEUROLOGICA SCANDINAVICA | 2007年 / 115卷 / 03期
关键词
Guillain-Barre; northwest Greece; polyneuropathy; seasonality;
D O I
10.1111/j.1600-0404.2006.00731.x
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Objective- We present the epidemiological and clinical-laboratory features of Guillain-Barre syndrome (GBS) in northwest Greece over a 9.5-year period. Materials and Methods- We studied all the patients with GBS who were admitted to our neurology inpatient service from January 1996 to May 2005 and compared them with previously published series. Results- Forty-six patients were hospitalized during this period. The average crude incidence rate was 1.22/100,000 populations per year, and males were more susceptible than females. There was a spring clustering, as 52.17% presented the syndrome during spring. The axonal type of GBS was recorded in 13.04% of the patients. The most frequent presenting symptom was dysesthetic numbness (52.17%). A large number of patients (56.52%) had up to three times the elevation of liver function values that resolved in a few weeks. Most patients had an excellent recovery and no deaths were recorded. Conclusions- In our series, there was no difference in the incidence rate and subtypes of GBS but there was a significant seasonality with spring clustering. A transient elevation of transaminases of undetermined etiology was noted in more than a half of our patients. Although seven patients (15.21%) had significant neurologic sequelae, no deaths occurred.
引用
收藏
页码:167 / 173
页数:7
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