The coiled coil-helix-coiled coil-helix proteins may be redox proteins

被引：24

作者：

Banci, Lucia ^{[1
,2
]}

Bertini, Ivano ^{[1
,2
]}

Ciofi-Baffoni, Simone ^{[1
,2
]}

Tokatlidis, Kostas ^{[3
,4
]}

机构：

[1] Univ Florence, Magnet Resonance Ctr CERM, I-50019 Florence, Italy

[2] Univ Florence, Dept Chem, I-50019 Florence, Italy

[3] Univ Crete, Dept Mat Sci & Technol, Iraklion 70013, Crete, Greece

[4] Univ Crete, Inst Mol Biol & Biotechnol, Fdn Res & Technol IMBB FORTH, Iraklion 70013, Crete, Greece

来源：

FEBS LETTERS | 2009年 / 583卷 / 11期

关键词：

Coil-coiled helix; Redox; MITOCHONDRIAL INTERMEMBRANE SPACE; CYTOCHROME-C-OXIDASE; DISULFIDE RELAY SYSTEM; HUMAN SCO1; COX17; IMPORT; MIA40; METALLOCHAPERONE; OXIDATION; PATHWAY;

D O I：

10.1016/j.febslet.2009.03.061

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A number of nuclear encoded proteins are imported in to the intermembrane space of mitochondria where they adopt a coiled coil-helix-coiled coil-helix (CHCH) fold. Two disulfide bonds formed by twin CX3C or CX9C motifs stabilize this fold. Some of these proteins are also characterized at their N-termini by the presence of two additional cysteine residues which can perform oxidoreductase or metallochaperone functions or both. This fold represents the most 'minimal' oxidoreductase domain described so far. (C) 2009 Federation of European Biochemical Societies. Published by Elsevier B. V. All rights reserved.

引用

页码：1699 / 1702

页数：4

共 34 条

[1] Mechanism of CuA assembly [J].

Abriata, Luciano A. ;

Banci, Lucia ;

Bertini, Ivano ;

Ciofi-Baffoni, Simone ;

Gkazonis, Petros ;

Spyroulias, Georgios A. ;

Vila, Alejandro J. ;

Wang, Shenlin .

NATURE CHEMICAL BIOLOGY, 2008, 4 (10) :599-601

[2] Erv1 mediates the Mia40-dependent protein import pathway and provides a functional link to the respiratory chain by shuttling electrons to cytochrome c [J].

Allen, S ;

Balabanidou, V ;

Sideris, DP ;

Lisowsky, T ;

Tokatlidis, K .

JOURNAL OF MOLECULAR BIOLOGY, 2005, 353 (05) :937-944

[3] Folding studies of Cox17 reveal an important interplay of cysteine oxidation and copper binding [J].

Arnesano, F ;

Balatri, E ;

Banci, L ;

Bertini, I ;

Winge, DR .

STRUCTURE, 2005, 13 (05) :713-722

[4] Solution structure of the Cu(I) and Apo forms of the yeast metallochaperone, Atx1 [J].

Arnesano, F ;

Banci, L ;

Bertini, I ;

Huffman, DL ;

O'Halloran, TV .

BIOCHEMISTRY, 2001, 40 (06) :1528-1539

[5] Solution structure of Cox11, a novel type of β-immunoglobulin-like fold involved in CuB site formation of cytochrome C oxidase [J].

Banci, L ;

Bertini, I ;

Cantini, F ;

Ciofi-Baffoni, S ;

Gonnelli, L ;

Mangani, S .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2004, 279 (33) :34833-34839

[6] Mitochondrial copper(I) transfer from Cox17 to Sco1 is coupled to electron transfer [J].

Banci, Lucia ;

Bertini, Ivano ;

Ciofi-Baffoni, Simone ;

Hadjiloi, Theodoros ;

Martinelli, Manuele ;

Palumaa, Peep .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2008, 105 (19) :6803-6808

[7] A structural-dynamical characterization of human Cox17 [J].

Banci, Lucia ;

Bertini, Ivano ;

Ciofi-Baffoni, Simone ;

Janicka, Anna ;

Martinelli, Manuele ;

Kozlowski, Henryk ;

Palumaa, Peep .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2008, 283 (12) :7912-7920

[8] Human Sco1 functional studies and pathological implications of the P174L mutant [J].

Banci, Lucia ;

Bertini, Ivano ;

Ciofi-Baffoni, Simone ;

Leontari, Iliana ;

Martinelli, Manuele ;

Palumaa, Peep ;

Sillard, Rannar ;

Wang, Shenlin .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2007, 104 (01) :15-20

[9] A hint for the function of human Sco1 from different structures [J].

Banci, Lucia ;

Bertini, Ivano ;

Calderone, Vito ;

Ciofi-Baffoni, Simone ;

Mangani, Stefano ;

Martinelli, Manuele ;

Palumaa, Peep ;

Wang, Shenlin .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2006, 103 (23) :8595-8600

[10] MIA40 is an oxidoreductase that catalyzes oxidative protein folding in mitochondria [J].

Banci, Lucia ;

Bertini, Ivano ;

Cefaro, Chiara ;

Ciofi-Baffoni, Simone ;

Gallo, Angelo ;

Martinelli, Manuele ;

Sideris, Dionisia P. ;

Katrakili, Nitsa ;

Tokatlidis, Kostas .

NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2009, 16 (02) :198-206

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