Patavine, a new arylnaphthalene lignan glycoside from shoot cultures of Haplophyllum patavinum

被引：25

作者：

Innocenti, G

Puricelli, L

Piacente, S

Caniato, R

Filippini, R

Cappelletti, EM

机构：

[1] Univ Padua, Dipartimento Sci Farmaceut, I-35121 Padua, Italy

[2] Univ Padua, Dipartimento Biol, I-35131 Padua, Italy

[3] Univ Salerno, Dipartimento Sci Farmaceut, I-84084 Salerno, Italy

来源：

CHEMICAL & PHARMACEUTICAL BULLETIN | 2002年 / 50卷 / 06期

关键词：

Haplophyllum; tissue culture; lignan; cytotoxicity;

D O I：

10.1248/cpb.50.844

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

A new arylnaphthalene lignan glycoside, patavine (1), together with five known lignans, justicidin B (2), diphyllin (3), tuberculatin (4), majidine (5), and arabelline (6) were isolated from shoot cultures of Haplophyllum patavinum. The structure of the new compound was elucidated by extensive one-dimensional (1D) and two-dimensional (2D) NMR experiments and mass spectrometry. The cytotoxicity of compounds 1, and 3-6 against LoVo human colon carcinoma cells was investigated.

引用

页码：844 / 846

页数：3

共 14 条

[1] CHEMICAL-CONSTITUENTS OF THE FLORA OF JORDAN .5B. 3 NEW ARYLNAPHTHALENE LIGNAN GLUCOSIDES FROM HAPLOPHYLLUM-BUXBAUMII [J].