A practice model for personalized healthcare with a public health genomics perspective

被引：4

作者：

Cesuroglu, Tomris

Karaca, Sefayet

Erge, Sema

机构：

来源：

PERSONALIZED MEDICINE | 2009年 / 6卷 / 05期

关键词：

chronic complex diseases; genetic predispositions; nutrigenetics; personalized healthcare; public health genomics;

D O I：

10.2217/PME.09.37

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Epidemiological and demographic transition has brought populations to an extended life expectancy in the 21st Century. The diseases of this century are complex, which stem mainly from the complex interactions of the human genome with lifestyle and environmental factors. These diseases are common, chronic and costly. Currently, the best-known prevention for complex diseases is adopting a healthy lifestyle. However, this is not achieved in many places in the world. Effective intervention models, including lifestyle changes for the prevention of these diseases, is urgently needed. in this report, we introduce a preventive healthcare model based on personalized healthcare. it is based on the application of public health genomics tools and concepts on an individual level, in order to stratify individuals according to risk groups, prevent diseases and detect them early.

引用

页码：567 / 577

页数：11

共 12 条

[1] Improved weight management using genetic information to personalize a calorie controlled diet [J].

Arkadianos, Ioannis ;

Valdes, Ana M. ;

Marinos, Efstathios ;

Florou, Anna ;

Gill, Rosalynn D. ;

Grimaldi, Keith A. .

NUTRITION JOURNAL, 2007, 6 (1)

[2] The new genetics - The new genetics in clinical practice [J].

Bell, J .

BMJ-BRITISH MEDICAL JOURNAL, 1998, 316 (7131) :618-620

[3] Implications of the Human Genome Project for medical science [J].

Collins, FS ;

McKusick, VA .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2001, 285 (05) :540-544

[4] Interleukin-1 genotype-selective inhibition of inflammatory mediators by a botanical: A nutrigenetics proof of concept [J].

Kornman, Kenneth ;

Rogus, John ;

Roh-Schmidt, Haeri ;

Krernpin, David ;

Davies, Audra J. ;

Grann, Kerry ;

Randolph, R. Keith .

NUTRITION, 2007, 23 (11-12) :844-852

[5] EPIDEMIOLOGIC TRANSITION - THEORY OF EPIDEMIOLOGY OF POPULATION CHANGE [J].

OMRAN, AR .

MILBANK MEMORIAL FUND QUARTERLY, 1971, 49 (04) :509-&

[6]

RENNER B, RISK PERCEPTION RISK

[7]

SAVAS BS, 2008, J NUTR NUTR, V1, P59

[8]

Simopoulos AP, 2004, WORLD REV NUTR DIET, V93, P1

[9]

*U WA PHGU IPHG, 2005, WORKSH REP ROCKF FDN

[10]

*US DEP HHS, PERS HLTH CAR IN PER

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