Preparation of monodisperse controlled release microcapsules

被引：21

作者：

Brandau, T ^{[1
]}

机构：

[1] BRACE GmbH, D-63755 Alzenau, Germany

来源：

INTERNATIONAL JOURNAL OF PHARMACEUTICS | 2002年 / 242卷 / 1-2期

关键词：

microspheres; microcapsules; microencapsulation; pharmaceuticals; food; cosmetics;

D O I：

10.1016/S0378-5173(02)00151-5

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Since the handling of many active agents in its pure form has many problems, microencapsulation is used to have better properties in the product. With the patented BRACE-Processes it is possible to encapsulate a very wide range of materials in monodisperse Microspheres or Microcapsules in a diameter range of 50-6000 mum with a very narrow size distribution. The Microsphere Units from BRACE can be customer tailored to the materials and all necessary specifications as FDA, GMP/GLP, EX, CIP, WIP etc. The throughput of the BRACE Microsphere Units ranges between 10 ml per h (small laboratory scale) up to over 1000 1 per h (production scale) while the production cost are very low, especially if compared directly to competitive processes as spray-drying or fluidized bed coating. (C) 2002 Elsevier Science B.V. All rights reserved.

引用

页码：179 / 184

页数：6