Formamicin, a novel antifungal antibiotic produced by a strain of Saccharothrix sp. .1. Taxonomy, production, isolation and biological properties

被引：22

作者：

Igarashi, M

Kinoshita, N

Ikeda, T

Nakagawa, E

Hamada, M

Takeuchi, T

机构：

[1] Institute of Microbial Chemistry, Shinagawa-ku, Tokyo 141

来源：

JOURNAL OF ANTIBIOTICS | 1997年 / 50卷 / 11期

关键词：

D O I：

10.7164/antibiotics.50.926

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Formamicin, an antifungal antibiotic, was isolated from the cultured broth of an actinomycete strain. The strain was isolated from a soil collected at Setagaya-ku, Tokyo, Japan, and identified as Saccharothrix sp. MK27-91F2. Formamicin was extracted with acetone from cultured mycelia and purified by silicagel and Sephadex LH-20 column chromatographies and CPC (Centrifugal liquid-liquid Partition Chromatography). Formamicin showed strong antimicrobial activity against phytopathogenic fungi.

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页码：926 / 931

页数：6

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