Antioxidant activity of Momordica charantia polysaccharide and its derivatives

被引：192

作者：

Chen, Fang ^{[1
]}

Huang, Gangliang ^{[1
]}

Yang, Zhiyuan ^{[1
]}

Hou, Yupeng ^{[1
]}

机构：

[1] Chongqing Normal Univ, Act Carbohydrate Res Inst, Chongqing Key Lab Inorgan Funct Mat, Coll Chem, Chongqing 401331, Peoples R China

来源：

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES | 2019年 / 138卷

关键词：

Momordica charantia polysaccharide; Derivatives; Preparation; Antioxidant activity;

D O I：

10.1016/j.ijbiomac.2019.07.129

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

070307 [化学生物学]; 071010 [生物化学与分子生物学];

摘要：

Momordica charantia polysaccharide (MCP) was extracted by hot water and chemically modified to obtain phosphorylated Momordica charantia polysaccharide (P-MCP) with degree of substitution 0.12 and sulfated Momordica charantia polysaccharide (S-MCP) with degree of substitution 0.45. The sugar content of the three polysaccharides was determined by phenol sulfuric acid method, 74.0%, 68.1% and 59.8% respectively. The scavenging ability of three polysaccharides to superoxide anion, hydroxyl radical and DPPH radical, as well as their anti-lipid peroxidation and reduction ability were determined. The results showed that the antioxidant activity of polysaccharides varied with different chemical modifications. (C) 2019 Elsevier B.V. All rights reserved.

引用

页码：673 / 680

页数：8

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