Incorporation of proteins into polymer materials by a novel supercritical fluid processing method

被引：59

作者：

Watson, MS

Whitaker, MJ

Howdle, SM ^{[1
]}

Shakesheff, KM

机构：

[1] Univ Nottingham, Sch Chem, Nottingham NG7 2RD, England

[2] Univ Nottingham, Sch Pharmaceut Sci, Nottingham NG7 2RD, England

来源：

ADVANCED MATERIALS | 2002年 / 14卷 / 24期

关键词：

D O I：

10.1002/adma.200290003

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The conventional solution and supercritical fluid processing were combined to prepare porous tissue engineering scaffolds that contained biologically active material for controlled release. The combination allowed the accurate dosing of the biological agent whilst retaining the advantages of supercritical fluid technology. The retention of biological activity throughout the supercritical CO2 processing using the enzyme ribonuclease A was also demsonstrated.

引用

页码：1802 / 1804

页数：3

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